Cimicifugae Rhizoma

What is Cimicifugae Rhizoma?

Cimicifugae Rhizoma is the rhizome of Cimicifugaheracleifoliakom, Cimicifugaheracleifoliakom, Cimicifugaheracleifoliakom, Cimicifugadahurica (Turcz.) Maxim. and CimicifugafoetidaL. Born in forests, hillside grasses and beside streams and ditch, it is mainly produced in Shaanxi, Sichuan, Qinghai, Yunnan, Henan and other places.The main components in Cimicifugae Rhizoma are triterpene polyoxygen compounds and chromones, phenolic acids, a variety of chromones, halamiol and halamidin. Among them, the identified structures are: Isoferulic acid, 3-Acetylcaffeic acid, Caffeicesterglucoside, Cimifugin, Cimifuginglucoside ), 6-Isoinosine (6-Isoinosine), Cimidahurine, Cimidahurinie, D-glucose, Sucrose, etc.Cimicifugae Rhizoma contains unique tetracyclic triterpene derivatives of cimigenol (cimigenol) and furan chromone compounds (cimicifugin, etc.), which have the effects of expelling wind and heat, and detoxification.
Cimicifugae Rhizoma, a herb with a long history of use in traditional Oriental medicine is reported to have anti-inflammatory, antioxidant, anti-complement and anticancer effects. The aim of the present study was to evaluate the effects of Cimicifugae Rhizoma extract on the osteogenic and adipogenic differentiation of human stem cells derived from gingiva.Stem cells derived from gingiva were grown in the presence of Cimicifugae Rhizoma at final concentrations of 0.1, 1 and 10 µg/ml. Cell proliferation analyses were performed at day 15. For osteogenic differentiation experiments, the stem cells were cultured in osteogenic media containing β-glycerophosphate, ascorbic acid-2-phosphate and dexamethasone, and osteogenic differentiation was evaluated by analysis of osteocalcin expression at 21 days.Analysis
AnalysisSpecificationResultTest methodPhysical Description

AppearanceYellow Brown PowderCompliesVisualOdorCharacteristicCharacteristicOrganolepticTasteCharacteristicCharacteristicOrganolepticParticle size98% through 80 mesh80 meshUSP32Chemical Test

Triterpenoid Saponins8% Min.8.2%HPLCLoss on drying2.0% Max0.5%USP32Ash Content1.0% Max0.4%USP32Heavy metals10ppm MaxCompliesUSP32

Cimicifugae Rhizoma Benefits:
1. It owns estrogenic effect,thus improving symptoms of female climacteric syndrome and postpartum syndrome;
2. Antibacterial and anticancer;
3. Anti-rheumatism, alleviating muscle pain and spasm;
4. Decreasing the cholesterol and blood pressure;
5. Delaying aging, especially the aging of skin and visceral organ;
Cimicifugae Rhizoma Applcation:
1.Applied in food field.it is widely used as functional food additive.
2.Applied in health product field, it is widely added into various kinds of health products with the function of preventing rheumatism, adjusting estrogen level and so on.
3.Applied in cosmetics field, it is widely added into various kinds of cosmetics with the function of delaying aging.
4.Applied in pharmaceutical field,it is widely added into the medicine which can used in treating arthritis and postpartum syndrome.

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