What is Maitake Extract?
Maitake extract has been shownTrusted Source to suppress tumor growth in mice. It can also increase the number of cells fighting against the tumor. This suggests that it could also be effective in managing cancer in humans when taken orally.The main active ingredient of maitake is Grifola frondosa proteoglycan. The polysaccharide component is mainly glucan, and the basic structure is β-(1→3) glucan with β-(1→6) branches. Contains a small amount of xylose and mannose.
An earlier study found Maitake Extract D-Fraction, which is an extract, to be efficient in killing human cancer cells. It was taken alongside a protein that also fights cancer and succeeded in increasing the protein’s effectiveness. Grifola frondosa extract uses the fruit body of Grifola frondosa Grifolafrondosus as raw material, and commercial extracts are usually standardized to contain 20% Grifola frondosa polysaccharide. Grifolafrondosus, also known as Polyrorusfrondosus, Polyrorusfrondosus, commonly known as Fang mushroom, is called “maitake mushroom” or “maitake mushroom” in Japan.
Its fragrant meat is crispy, and its protein content is 1/3 higher than that of shiitake mushrooms. The human body must have amino acid content. High, rich in vitamins and minerals, popular in some countries and regions such as Japan, Europe and America. Grifola frondosa also has a high medicinal value. Grifola frondosa polysaccharide extracted from Grifola frondosa has the strongest anti-tumor activity among all fungal bioactive substances, and most of the fungal polysaccharide preparations are not effective when taken orally. With the exception of flower polysaccharides, Grifola frondosa D-component is currently a research and development focus in the United States and Japan.
Maitake extract: standardised to 30% polysaccharidesBasic Information:
Product nameMaitake ExtractLatin nameGrifola frondosaPlace of OriginJapan, ChinaHarvest season
Part usedWhole herbExtraction TypeSolvent ExtractionActive IngrdientsPolysaccharidesCas No/Molecular Formula/Formula Weight/SynonymsPolyporus fuliginea, chestnut mushroom, lotus flower, leaf fungus, thousand bacteriumTest MethodUVFormula Structure/
Maitake Extract Benefits:
Maitake mushroom contains chemicals which might help fight tumors and stimulate the immune system. There is some evidence that it can lower blood pressure, improve cholesterol levels, lower blood sugar levels, and reduce weight in rats, but this has not been shown for humans yet.
1.CholesterolPreliminary evidence shows that Maitake Mushroom Extract may help lower cholesterol levels, notes CoxHealth Medical Center. A study on laboratory animals published in the October 2011 issue of the “Journal of Agriculture and Food Chemistry” found that four weeks of supplementation with maitake mushroom extract lowered liver cholesterol levels. Researchers concluded that maitake exerted its effects at the genetic level by increasing activity of genes in the liver that promote lipid transport. By contrast, Hypsizigus marmoreus, or beech mushroom, another mushroom tested in the study, did not show cholesterol-lowering effects.
2.Blood SugarMaitake Extract may help manage blood sugar levels and prevent diabetes, according to a study published in the April 2007 issue of the “Journal of Pharmacy and Pharmacology.” A polysaccharide molecule in maitake, called MT-alpha-glucan, decreased fasting blood sugar and insulin levels and increased levels of glycogen, a short-term storage form of glucose, in the liver. Maitake also increased the ability of insulin to bind to liver cells and improved pancreatic function. Researchers concluded that maitake may be useful for prevention and management of diabetes by decreasing insulin resistance.
3.Immune FunctionImmune benefits of maitake extract include modulation of cytokines, molecules produced by white blood cells that activate the immune response, according to the University of Wisconsin Botany Department. Maitake exerts its effects by binding to the cell membranes of white blood cells known as macrophages and either activating or inhibiting release of cytokines. A study published in the Summer 2004 issue of the “Journal of Medicinal Food” found that D-fraction, a polysaccharide extract of maitake, activated several types of immune cells and molecules, including T-helper cells, macrophages and interleukins. Researchers concluded that maitake may offer immune benefits that help protect against infection.
4.CancerMaitake Extract D-fraction may inhibit cancer development and spread and also make chemotherapy drugs more effective, according to Dr. Shari Lieberman, author of the book “Maitake Mushroom Extract and D-Fraction.” A study published in the June 2011 issue of the “Journal of Medicinal Food” found that maitake D-fraction promotes apoptosis — programmed cell death — in breast cancer cells. Maitake extract interfered with energy production in cancer cells, a discovery which, researchers note, will help scientists target potential cancer prevention and treatment approaches.
Maitake Extract Application:
(1)Applied in pharmaceutical field, it is usually made into tablets, soft capsule, injectio, etc. to treat acute bacillary dysentery, gastroenteritis, cat fever, amygdalitis, faucitis, bronchitis, pneumonia, phthisis and so on.
(2)Applied in veterinary field, it is made into pulvis to treat acute bacillary dysentery, gastro-enteritis and pneumonia of poultry and livestock.
Undersun’s Grifola frondosa ExtractCompetitive advantage:We are a factory which has a professional team, could supply you qualified products, 24 hours online service and quick response. Small quantity and special customized products could be accept!Quality Standard:Conform to QB standards.
Production process flow chart:
Formulation solution:Grifola frondosa polysaccharides could be used into food and beverage.
Packing & Storage :
Packing: 25Kg/Fiber Drum, double plastic bag inside.1Kg/Bag, aluminum foil bag vacuum packingOr customized.
Storage: Kept away from strong light and heat.
Shelf Life: 24 months for powder
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