Matrine

What is Matrine?Matrine is an alkaloid found in plants from the Sophora family. It has a variety of pharmacological effects, including anti-cancer effects, and action as a kappa opioid receptor agonist.
Matrine possesses strong antitumor activities in vitro and in vivo. Inhibition of cell proliferation and induction of apoptosis are the likely mechanisms responsible for matrine’s antitumor activities. It is a component of the traditional Chinese medical herb Sophora flavescens Ait. the related compound oxymatrine have an antifeedant effect against Formosan subterranean termite.Matrine is the dried root of Sophora flavescens, plants, fruits and other organic solvents extracted by ethanol is made of alkaloids. Usually Sophora Alopecuroides, the main ingredients are matrine, sophora alkali, oxysophora alkali, Sophoridine and other alkaloids, oxymatrine content of the highest.Other sources for the Sophora Tonkinensis and Sophora bean root part? Pure appearance of white powder.
Matrine is an active alkaloid, extracted from a traditional Chinese herbs of the Sophora family. It has been reported for its anti-inflammatory and neuroprotective effects. It was demonstrated that the antinociceptive effects of (+)-it was mediated by mu- and kappa-opioid receptors. It could dose-dependently restore the balance of Th17/Treg cytokines and attenuate the cognitive impairment in Alzheimer’s disease rats. Sophora flavescens and its bioactive compound, matrine alleviated caffeine-induced hyperactivity and promoted non-rapid eye movement sleep by activating ventrolateral preoptic nucleus neurons and modulating serotonergic transmission. Clinical trial results indicate, that intramuscular it may be an economical, efficacious, safe drug for the treatment of chronic hepatitis B. Matrine injection may be used to protect the liver function for patients with primary hepatic carcinoma after trans-artery chemo-embolization (TAE), to relieve the liver cells damage, and to improve the tolerance of TAE, so as to perform the next TAE in time.

Analysis

Product NameMatrineSpecification70% By titritionAppearancebrown liquildPart UsedRootTest methedTraditional chinese medicine/Natural PlantSolubilitywater solubleSolubility rate≥95%Loss on Drying≤5%ConclusionConform with specificationPackaging DescriptionSealed export grade drum & double of sealed plastic bagStorageare in a cool dry place and keep away from strong light and heat

Appication:1). Applied in agriculture field, it is a natural plant pesticides and insecticides, insect pests that once touched the drug will suffocate;(2). Applied in pharmaceutical field, injection on the treatment of chronic persistent hepatitis have a good effect;(3). Applied in cosmetic field, it has good effect of anti-cancer

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