NMN Pure

WHAT is NMN Pure?
Nicotinamide mononucleotide (NMN pure) is one of the intermediates in NAD+ biosynthesis and is a bioactive nucleotide formed by the reaction between a phosphate group and a nucleoside containing ribose and nicotinamide (NAM) (Poddar et al., 2019). NAM is directly converted to NMN by nicotinamide phosphoribosyltransferase (NAMPT). The molecular weight of NMN is 334.221 g/mol (Poddar et al., 2019). There are two anomeric forms of NMN named alpha and beta, and the latter is the active form (Poddar et al., 2019).
NMN pure is found in various types of natural foods, such as vegetables, fruits, and meat. Edamame and broccoli contain 0.47–1.88 and 0.25–1.12 mg NMN/100 g, respectively, whereas avocado and tomato contain 0.36–1.60 and 0.26–0.30 mg NMN/100 g, respectively. However, raw beef only contains 0.06–0.42 mg NMN/100 g (Mills et al., 2016). Recent preclinical studies have demonstrated that the administration of NMN could compensate for the deficiency of NAD+, and NMN supplementation was able to effect diverse pharmacological activities in various diseases.
In this review, NAD+ biosynthesis pathways and the possible reason for its age-related decline are described. Also, a summary of studies on the role of NAD+ deprivation in causing human diseases and how the application of pure NMN could have positive effects on those diseases is provided.Certificate of Analysis:
ItemsStandardsResultsPhysical Property

DescriptionWhite PowderCompliesAssay98%99.20%Mesh Size100 % pass 80 meshCompliesAsh≤ 5.0%2.85%Loss on Drying≤ 5.0%2.65%Chemical Property

Heavy Metal≤ 10.0 mg/kgCompliesPb≤ 2.0 mg/kgCompliesAs≤ 1.0 mg/kgCompliesHg≤ 0.1mg/kgCompliesMicrobiological Property

Residue of PesticideNegativeNegativeTotal Plate Count≤ 1000cfu/gCompliesYeast&Mold≤ 100cfu/gCompliesE.coilNegativeNegativeSalmonellaNegativeNegativeNMN Pure Benefits:
Endurance and Muscle StrengthDecreased physical endurance and muscle strength are often considered to be “inevitable” symptoms of the normal aging process. However, recent animal research indicates that NMN may prevent these declines in aging mice. In fact, one study found that consumption of NMN enhanced endurance and muscle strength in aged mice to such a degree that they became as healthy as their much-younger peers! [1, 2]
AgingEndurance and muscle strength are not the only physical symptoms impacted by the aging process; body weight, energy metabolism, blood lipids, insulin sensitivity, and vision are also adversely affected by the aging process. Excitingly, NMN supplementation has been found to suppress age-associated weight gain, enhance metabolism, improve insulin sensitivity and plasma lipid levels, benefit vision, and prevent adverse alterations in gene expression in aging mice. [2] These effects highlight the therapeutic potential of NMN as a beneficial anti-aging intervention for humans.
Alzheimer’s Disease and Neurological FunctionAlzheimer’s disease is on the rise, with nearly 5.7 million Americans living with the disease; this number is projected to rise to 14 million by 2050. Dietary and lifestyle changes are crucial for preventing and slowing the progression of Alzheimer’s disease. NMN may help bolster the beneficial effects of dietary and lifestyle changes in Alzheimer’s disease prevention by preserving the health of the brain. NMN inhibits the buildup of amyloid-beta, an abnormal protein implicated in the adverse brain changes characteristic of Alzheimer’s disease, while also decreasing synaptic loss and brain inflammation. [3] These effects slow down the process of brain degeneration and may even help reverse the progression of Alzheimer’s disease.
The neurological benefits of NMN are not limited to Alzheimer’s disease; NMN also maintains the brain’s population of neural stem cells and attenuates brain injury after head trauma. [4, 5] These findings suggest that NMN may have significant therapeutic benefits for athletes who have suffered concussions, and other individuals recovering from head injuries.Heart DiseaseThe human heart requires a continuous supply of ATP to fuel its muscular contractions and sustain life. Interruptions in the heart’s ATP supply can impair cardiac and vascular function and contribute to the development of cardiovascular disease. By enhancing the biosynthesis of NAD+, an essential substrate in ATP-producing reactions, NMN boosts cardiac ATP levels and significantly improves heart health. In fact, supplementation with NMN may even prevent myocardial infarctions and heart failure! [6] Importantly, NMN pure also reduces arterial aging and vascular dysfunction, two phenomena that play crucial roles in the pathogenesis of cardiovascular disease. [7]
Diabetes and Metabolic SyndromeIn pancreatic beta cells, NAD+ regulates insulin secretion in response to the ingestion of dietary glucose. [8, 9] NAD+ also governs insulin activity and glucose homeostasis in skeletal muscle, the liver, and adipose tissue. Research indicates that the normal biosynthesis of NAD+ is severely compromised in diabetic individuals, leading to insulin resistance and glucose intolerance.By restoring NAD+ levels in skeletal muscle, the liver, and adipose tissue, NMN improves insulin sensitivity and may help reverse the course of diabetes. NMN also corrects dyslipidemia, a condition in which cholesterol and triglycerides are elevated in the bloodstream.

DNA RepairYour DNA serves as the blueprint for your body’s physiological function. When DNA expression goes awry due to factors such as an unhealthy diet, environmental toxins, and aging, your body’s blueprint is intrinsically altered; this disrupts normal body function and contributes to the development of chronic health conditions such as cancer, diabetes, and neurological dysfunction. Pure nmn helps prevent adverse changes in gene expression by repairing damaged DNA. [13]
WeightWeight gain and weight loss resistance are common struggles for countless Americans. NMN is a powerful nutraceutical ally in weight loss efforts because it reverses insulin resistance, improves glucose tolerance, and ameliorates mitochondrial dysfunction, three factors that contribute to stubborn weight issues. [14, 15]
Human TrialsWhile most of the available research on NMN involves animal studies, human clinical trials have been undertaken, and the results are expected to be released within the next year. In the meantime, the plethora of beneficial effects demonstrated by NMN in animal studies, and the complete lack of adverse effects, suggests that NMN supplementation may be a valuable tool to add to your healthy lifestyle today!
Application of NMN Pure:Cosmetic raw material:NMN itself is a substance in the body of cells, and its safety as a drug or health care product is high, and NMN is a monomer molecule,it’s anti-aging effect is obvious, so it can be used in cosmetic raw materials.
Health care products:Niacinamide mononucleotide (pure NMN powder) can be prepared by yeast fermentation, chemical synthesis or in vitro enzymatic catalysis. It widely used in the health care industry.The Best NMN Pure SupplierUndersun enjoys long term relationships with our clients because we focus on customer service and providing great products. If you are interested in our products, we are flexible with the customization of orders to suit your specific need and our quick lead time on orders guarantees you’ll have great tasting our products on-time.
We also focus on value-added services. We are available for service questions and information to support your business.

We specialize in NMN bulk powder for several years, we supply products with competitive price, and our product is of the highest quality and undergoes strict, independent testing to ensure that it is safe for consumption around the world.
Where to buy NMN Pure?
The best quality NMN Pure is carefully prepared without the use of excess heat and chemicals. Always choose a product which is natural and pure and has no added fillers or preservatives. A concentrated extract provides a powerful way to get a larger dose of NMN’s nutrients in each dose. We offer a 10:1 concentrated extract powder which is ten times more powerful than the raw material. NMN Pure Powder should be kept in airtight packing and stored in a dry, dark and cool place.
Just send email to mark@dongyuanbiotech.com, or submit your requirement in bottom form, we are of service at any time!Production processes:Coconut oil/ Palm Kernel Oil→Emulsified homogenization→Embedding reinforcement→Cold spray drying→first rejuvenation→Secondary recombination dry forming→inspection→package→in stock
OEM PACKAGING AND PRIVATE LABELNMN Powder could be used into sport beverage, baby supplement and pet supplement.Packing & Storage :Packing: 25Kg/Fiber Drum, double plastic bag inside.1Kg/Bag, aluminum foil bag vacuum packing Or customized. Storage:Kept away from strong light and heat. months for powder.
ORGANIC CERTIFICATION OF NMN POWDER
FAQ:Do You Want To Place An Order With Us Now？Please contact with : mark@dongyuanbiotech.com

Q1:Can I get some samples of Bulk NMN?A:Yes, we can supply the free sample, you just pay for freight.Q2:How to start orders or make payments?A:Proforma invoice will be sent first after confirmation of order, enclosed our bank information. Payment by T/T, Western Union or Escrow.Q3:What’s your MOQ?A:Our MOQ is 1kg. But usually we accept less quantity such as 100g on the condition that sample charge is 100% paid.Q4:How about delivery time?A:About 3-5 days after payment confirmed.Q5:Is there a discount?A:Different quantity has different discount.Q6:How do you treat quality complaint?A:First of all, our quality control will reduce the quality problem to near zero. If there is a real quality problem caused by us, we will send you free goods for replacement or refund your loss.

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