Piperine Extract

Product Name:piperine extract powder

Botanical Source: Piper nigrum L.

Part Used: Seed

Active Ingredients: Piperine

CAS ID: 94-62-2

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Certifications: ISO,KOSHER,Halal,Organic;

Packing :25kgs/drum or 1kg/bag;

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What is Piperine Extract?Piperine, along with its isomer chavicine, is the alkaloid responsible for the pungency of black pepper and long pepper. It has been used in some forms of traditional medicine.Piperine extract and is the only product able to increase the bioavailability of nutritional compounds that is supported by proper testing and certification. Pure piperine extract is also known as a thermonutrient and may assist by enhancing internal processes within the human or animal. This natural ingredient may be added to foods and beverages or smoothies and green drinks. It is a light to medium gray powder and has no fillers or binders, additives or preservatives. Various sizes available for personal use and quantity discounts available on bulk-packed foods and food powders for commercial uses.Basic Information:Product namePiperineLatin namePiper Nigrum L.Harvest seasonAutumnPart usedSeedsActive IngrdientsPiperineCas No394-62-2Molecular FormulaC17H19NO3Test MethodHPLCApplicationDietary Supplement Piperine Extract Benefits:Pepper is the most basic ingredient in Indian medicine and is used to treat many diseases. Pharmacological studies have proved many of their traditional medicinal effects such as: analgesic and antipyretic effects, antioxidant effects, antibacterial effects, etc. Piperine is an effective ingredient of pepper. Piperine has a wide range of pharmacological effects, and has been found to have anti-oxidation, immune regulation, and anti-tumor effects.
1. Anti-tumor There are many reports on the anti-tumor effects of piperine. Studies have found that piperine extract can inhibit lung metastasis induced by B16F-10 melanoma, significantly reduce tumor formation, and prolong the survival of tumor-bearing mice. This shows that piperine has anti-tumor metastasis effects. Studies have found that oral piperine can significantly reduce the lipid peroxidation level, nucleotide content and polyamine synthesis in mice with benzopyrene-induced lung cancer. Its inhibitory mechanism is to protect protein from damage and inhibit cell proliferation. In the melanoma cell model, piperine can effectively inhibit the gene expression of ATF-2, NF-kappab and inflammatory cytokines.

2. AntioxidantBased on the DPPH-free radical generation system, the ability of piperine to scavenge this kind of free radicals in anhydrous ethanol medium was studied. Its ability to scavenge free radicals can indicate the strength of its antioxidant capacity. Studies have shown that piperine has a certain antioxidant activity, its antioxidant capacity is equivalent to 60.05% of vitamin C, and it exists stably in acidic media.

3. Effects on the central nervous systemAt present, studies have proved that piperine has various effects such as sedation, hypnosis, anticonvulsions, skeletal muscle relaxation and antidepression. The study of the effect of pure piperine extract on animal sleep has found that piperine can significantly reduce the autonomous activities of mice, and significantly Extending the sleep time of mice induced by sodium pentobarbital can also significantly increase the deep sleep of rabbits. The mechanism may be related to the increase of serotonin content in the brain.

4. Immune regulationThe immunotoxicological study of piperine extract showed that the mice had no obvious toxic effects when gavage piperine extract for five consecutive days, and the liver weight increased normally. When studying the effect of piperine on thymocytes, it was found that piperine can inhibit the production of reactive oxygen species (ROS) and increase the content of glutathione (GSH), and inhibit cell apoptosis and changes in the phenotype of thymus-dependent lymphocytes.

5. Reduce inflammationPure piperine extract can reduce inflammation and pain. Oral piperine at a dose of 50 mg/kg can significantly reduce the occurrence of inflammation. Piperine has an anti-inflammatory effect. Piperine and its congeners can be absorbed through the skin, so it can act on subcutaneous tissues, nerves and blood vessels. In addition, pharmacological studies have shown that piperine can prevent atherosclerosis, lower blood lipids, have anticonvulsant and antiulcer activities, protect the liver, and will not damage the function of the testicles. And whether in the body or outside of the body, piperine can also slow down the peristalsis of the intestines. The effect of piperine on the nervous system and sexual organs reflects its anti-convulsant and vasodilator properties.
Application:1. As pharmaceutical raw materials for arthritis, rheumatism, anti-inflammation, detumescence and so on, it is mainly used in pharmaceutical field;2. As products effective ingredients for improving blood circulation and soothing the nerves, it is mainly used in health product industry;3. As active ingredients of skin care products, it is mainly used in cosmetic industry.
Piperine Dosage:In North America, an average diet contains about 360 mg of black pepper per day or about 18–32 mg of piperine. Black pepper consists of 5%–9% piperine.Doses of 5–10 mg of piperine are given concomitantly with nutritional supplements (such as turmeric and resveratrol) to enhance absorption.
The Best Piperine Extract SupplierUndersun enjoys long term relationships with our clients because we focus on customer service and providing great products. If you are interested in our products, we are flexible with the customization of orders to suit your specific need and our quick lead time on orders guarantees you’ll have great tasting our products on-time.We also focus on value-added services. We are available for service questions and information to support your business.
Why Choose Undersun Piperine Extract?Undersun specialize in pure piperine extract for several years, we supply products with competitive price, and our product is of the highest quality and undergoes strict, independent testing to ensure that it is safe for consumption around the world.
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