Senna Leaf Extract

What is Senna Leaf Extract?Senna Leaf Extract is a kind of plant raw material extracted from Cassia angustifolia Vahl., the main raw material of Senna Leaf dry leaflet, using the extraction technology of plant active ingredients. Its main active ingredients are Sennoside A and B (Sennoside A and B), and it contains anthraquinone derivatives such as emodin, aloe emodin, emodin and other glycosides.Senna leaf extract is prepared from a large genus of flowering plant Cassia angustifolia Vahl in the fabaceae family on the tropics. It has been used for centuries in folk medicine as a laxative and stimulant. Senna is also included in several herbal teas, used for purging and in weight loss. The active components sennoside in senna leaf extract are anthraquinone derivatives and their glucosides, referred to as senna glycosides or sennosides.Senna leaf extract weight loss belongs to a large genus of flowering plants found throughout the tropics, commonly used species being Cassia acutifolio (Alexandrian senna) and C. angustifolio (Indian or Tinnevelly senna). Extracts of the leaves, flowers and fruit of senna have been used for centuries in folk medicine as a laxative and stimulant. Senna is also included in several herbal teas, used for purging and in weight loss. The active components in it is anthraquinone derivatives and their glucosides, referred to as senna glycosides or sennosides.Basic Information:PARAMETERSPECIFICATIONDescriptionLight to dark brown Color PowderOdour & TasteCharacteristicIdentificationPositive for Sennoside by TLCBulk Density ( tapped)0.30 to 0.80 gm/mlLoss on dryingNMT 5.0 %pH of 1% Solution5.0 – 8.0Particle Size100 % Pass through 40 meshAssay
Total sennosides by UV (As is)NLT 20 %Microbial Analysis
Total Plate CountNMT 1000 cfu/gmYeast and MouldNMT 100 cfu/gmColiformsAbsentE. coliAbsentSalmonella spp.AbsentShigellaAbsentHeavy MetalNMT 10 ppmSenna Leaf Extract Benefits:

It is used to treat constipation and also to clear the bowel before diagnostic tests such as colonoscopy. Senna is also used for irritable bowel syndrome (IBS), anal or rectal surgery, tears in the lining of the anus (anal fissures), hemorrhoids, and weight loss. Senna fruit seems to be gentler than senna leaf.1.ConstipationThe most famous use of this herb is as a laxative and a purgative. It is now known that the laxative effects of Senna are due to anthraquinone glycosides known as sennosides. These compounds stimulate intestinal contractions that lead to the rapid expulsion of waste matter.
Senna may also be able to soften the stool by assisting the large intestine to absorb more water and adding bulk to faeces. This allows for bowel movements that are quick and smooth as waste passes through the large intestine.2.Colon CleanseSenna Leaf Extract is often used to clear the bowel before diagnostic tests such as colonoscopies. Cleansing the colon is believed to improve nutrient uptake and support overall colon health.

3.Anti-ParasiticSenna Leaf Extract also works as an effective vermifuge to destroy parasites and expel worms from the intestinal tract. It works best when combined with other anthelmintic herbs (used in the treatment of roundworm), such as ginger or fennel. These herbs increase regularity and reduce the chance of bowel cramps due to Senna’s strong action.

3.Digestive HealthIn the case of indigestion, Senna contains natural enzymes that help to restore gastric juice secretions in the stomach. Senna, if used in the proper dosage for certain periods of time, has shown potential in reducing irritability in the intestines by improving overall digestion.Senna also contains the anti-inflammatory compound resveratrol which can help to soothe inflammation in the gastrointestinal tract.
4.Skin HealthSenna Leaf Extract contain essential oils and tannins that help to alleviate skin inflammation. With a strong antibacterial activity, they can be made into a compress which can be applied to wounds and burns.

Acetone and ethanol – other compounds present in Senna – can fight the microorganisms that cause acne. Senna also helps to reduce sebum production and increase cell regeneration and collagen production.senna leaf for weight lossSenna is frequently marketed as a weight loss tool, but there’s no evidence to support this effect. Due to its long-term health risks, you should not use senna to lose weight.Senna Leaf Extract DoseDosage Forms and StrengthsTablet, extended-release8.6 mg
15 mg25 mgChewable tablet10 mg
15 mgLiquid: 8.8 mg/5mLConcentrated oral drops: 8.8 mg/mLSyrup: 8.8 mg/5mLSenna leaves:454gDosage Considerations – Should be Given as Follows:Constipation
Adult: 15 mg orally once daily; not to exceed 70-100 mg/day divided every 12 hoursNot for use more than 1 weekSenna Leaf Extract362-1056 mg orally once/dayPediatric:Children 2-6 years: 4.3-17.2 mg/day orally; not to exceed 17.2 mg/dayChildren 6-12 years: 6-50 mg/day orally; not to exceed 50 mg/dayChildren over 12 years: 12-100 mg/day orally; not to exceed 100 mg/dayNot for use more than 1 weekSenna Leaf Extract2-6 years: 166.5-666 mg/day orally6-12 years: 333-999 mg/day orallySenna Leaf Extract Uses:1.It can clear stomach and purge heat, defaecate and use diuretic of hydragogue to alleviate water retention;
2.It also helps to temporarily prevent fluid from being absorbed from the large intestine, thus contributing to softer stools;
3.It is used in the treatment of constipation, working through a stimulation of intestinal peristalsis.
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