Silybum Marianum Extract

What is Silybum Marianum Extract?Silybum marianum extract is a plant whose numerous segments, fundamentally a flavanolignan substance known as silymarin, have articulated cancer prevention agent and skin-quieting capacity. Silymarin happens in milk thorn products of the soil, and assists shield with cleaning from the obvious impacts of UV light introduction (obviously, you actually need an expansive range sunscreen).
Silymarin likewise has research on its part in interfering with pathways in skin that lead to stains on skin’s surface, while that and different mixes in milk thorn appear, in any event in a lab setting, to inhibitorily affect chemicals that corrupt collagen.
So, it’s an amazing cancer prevention agent to find in healthy skin items, especially those that address ecological stressors.
Silybum marianum extract have been used since ancient Rome as treatment for various disorders, including those of the liver, and studies have suggested plausible mechanisms whereby they could be beneficial in selected settings.58 Milk thistle seeds contain approximately 60% silymarin, which is a mixture of six flavonolignan isomers. Two isomers, silibinin A (Fig. 50-3) and silibinin B, comprise about half of silymarin.59 Administration of oral formulations of milk thistle extract such as Legalon results in plasma Cmax values for silibinin A and B of 100 to 600 ng/mL, and the half-life is approximately 1 to 2 hours.

Basic Information:Product nameSilybum Marianum Extract(Milk thistle extract)Latin nameSilybum marianum (Linn.) Gaertn.Place of OriginLiaoning,Inner Mongolia ChinaPart usedSeedExtraction TypeSolvent Extraction (Acetone/Ethanol)Active IngrdientsSilymarin/Silybin, Isosilybin, Silychristin, SilydianinCas No65666-07-1 22888-70-6Molecular FormulaC25H22O10Formula Weight482.44SynonymsSilybum marianum ,cardus marianus, milk thistle, blessed milk thistle, Marian Thistle, Mary Thistle, Saint Mary’s Thistle, Mediterranean milk thistle,variegated thistle , Scotch thistle,SilymarinTest MethodHPLC /UVFormula StructureSpecifications10:1 Brown yellow powderSilymarin 45%-60%, USP Yellow powder
Silymarin 80%&Silybin+Isosilybin 30% Yellow powder
Silybin 70%-98% White powder
Water soluble Silymarin 10%-45% brown yellow powder
ApplicationMedicine, food additive, dietary supplement, sports nutrition

AnalysisSpecificationResultTest methodAssay(Silymarin)80.00% Min80.26%UVAppearanceLight yellow powderCompliesVisualHeavy metals20ppm MaxCompliesAASArsenic(As)2ppm MaxCompliesAASMercury(Hg)1ppm MaxCompliesAASMicrobiology

Total Plate Count1,000cfu/g MaxCompliesAOACYeast & Mold100cfu/g MaxCompliesAOACSalmonellaNegativeNegativeAOAC

Silybum Marianum Extract Benefits:

1.Helpful in treating mental conditions – Recent studies have revealed that silybum marianum extract has neuroprotective effects on the body.
2.Treating spikes in blood glucose levels – A double-blind clinical trial showed that patients who consumed 200 mg of silymarin thrice daily for about four months had drastic declines in their blood sugar levels when compared with patients who consumed only a prescribed anti-diabetic drug.
3.Promoting the production of breast milk – One clinical study was conducted on 50 lactating women who consumed 420 mg of silymarin daily for 63 days.
4.Preventing bone diseases – Age-related bone disorders like osteoporosis result from an imbalance between osteoclastic and osteoblastic activity. Silymarin has been shown to promote alkaline phosphatase activity of osteoblasts and inhibit tartrate-resistant acid phosphatase activity of osteoclasts.
5.Benefits in treating cancer – The antioxidant effects of milk thistle may have anti-neoplastic effects. Some animal model studies show that silibinin (a component of milk thistle) can inhibit signaling pathways of cancer cells in preclinical studies.
6.Beneficial effects in treating acne – A randomized clinical trial conducted on 56 patients showed that milk thistle may be helpful in treating acne vulgaris.

Silybum Marianum Extract Applications:
1. Silybum marianum extract is used as food and beverage ingredients.2. As Healthy Products ingredients.
3. As Nutrition Supplements ingredients.4. As Pharmaceutical Industry & General Drugs ingredients.
5. As a health food and cosmetic ingredients.

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Q1:Can i get some samples?A:Yes, we can supply the free sample, but the shipping cost be paid by our customers.Q2:How to start orders or make payments?A:Proforma invoice will be sent first after confirmation of order, enclosed our bank information. Payment by T/T, Western Union or Escrow(Alibaba).Q3:What’s your MOQ?A:Our MOQ is 1kg. But usually we accept less quantity such as 100g on the condition that sample charge is 100% paid.Q4:How about leading time?A:Leading time: About 3-5 days after payment confirmed. (Chinese holiday not included)Q5:Is there a discount?A:Different quantity has different discount.Q6:How do you treat quality complaint?A:First of all, our quality control will reduce the quality problem to near zero. If there is a real quality problem caused by us, we will send you free goods for replacement or refund your loss.

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